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We report the syntheses of monomers to incorporate fluorescein and methyl red within the sequence and at the termini of modified oligonucleotides. These monomers have been used in the solid-phase synthesis of fluorogenic oligonucleotides for genetic analysis and the study of multi-stranded nucleic acid structures.


Journal article


Org Biomol Chem

Publication Date





2267 - 2275


Azo Compounds, DNA Primers, Fluorescein, Fluorescent Dyes, Models, Biological, Models, Chemical, Nucleic Acid Probes, Oligonucleotides, Polymerase Chain Reaction