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Rapid controlled self-assembly makes DNA ideal for building nanostructures. A problem using hybridized intermediates in hierarchic assembly is their thermodynamic lability. We demonstrate a click-fixation technology by which robust hexagonal DNA modules can be made. This principle is applicable to a wide variety of DNA nanoconstructs.

Original publication

DOI

10.1039/c001513j

Type

Journal article

Journal

Chem Commun (Camb)

Publication Date

07/06/2010

Volume

46

Pages

3714 - 3716

Keywords

DNA, Electrophoresis, Polyacrylamide Gel, Fluorescence Resonance Energy Transfer, Nanostructures, Nucleic Acid Hybridization, Oligonucleotides