A new fixation strategy for addressable nano-network building blocks.
Lundberg EP., El-Sagheer AH., Kocalka P., Wilhelmsson LM., Brown T., Nordén B.
Rapid controlled self-assembly makes DNA ideal for building nanostructures. A problem using hybridized intermediates in hierarchic assembly is their thermodynamic lability. We demonstrate a click-fixation technology by which robust hexagonal DNA modules can be made. This principle is applicable to a wide variety of DNA nanoconstructs.