HyBeacons®: A novel DNA probe chemistry for rapid genetic analysis
French DJ., McDowell DG., Thomson JA., Brown T., Debenham PG.
The analysis of single nucleotide polymorphisms (SNPs) and short tandem repeats (STRs) has proven extremely valuable in both healthcare and forensic sectors. Such analyses have historically been time-consuming, laborious and confined to specialist analytical laboratories. The HyBeacon probe technology presented here provides a rapid method for the detection and identification of specific nucleic acid sequences, which could be employed away from the laboratory in primary healthcare and certain forensic settings. © 2006.