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The mutagenic lesion 3,N4-etheno-2′-deoxycytidine (εdC) greatly destabilises DNA when paired with each of the natural bases although the solution structure of a duplex containing a εC: A pair shows that the lesion does not greatly disrupt base pairing in the duplex.

Original publication




Journal article


Journal of the Chemical Society, Chemical Communications

Publication Date



2241 - 2242