Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

By the H-phosphonate approach on a solid support we have synthesised a 28-mer homopolymer of 2'-deoxycytidine (SdC28), a 28-mer phosphorothioate oligodeoxynucleotide (Srev) complementary to the HIV-1 regulatory gene and a number of its base modified derivatives. Anti HIV-1 activity of S-dC28 and Srev in chronically infected T-cells was studied. Melting temperatures of rev-comp rev and Srev-comp rev were also measured. © 1991, Taylor & Francis Group, LLC. All rights reserved.

Original publication




Journal article


Nucleosides and Nucleotides

Publication Date





555 - 561