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N(α)-t-Butoxycarbonyl-N(π)-benzyloxymethyl-L-histidine (1) and N(α)-t-butoxycarbonyl-N(π)-4-bromo-benzyloxymethyl-L-histidine (2) have been prepared and shown to be suitable derivatives for peptide synthesis with histidine; the synthetic intermediates had convenient physical properties, no side reactions were encountered, and the final deprotection proceeded smoothly under mild conditions.

Original publication

DOI

10.1039/C39810000648

Type

Journal article

Journal

Journal of the Chemical Society, Chemical Communications

Publication Date

01/01/1981

Pages

648 - 649