Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Osteoblasts are an important cellular component of the bone microenvironment controlling bone formation and hematopoiesis. Understanding the cellular and molecular mechanisms by which osteoblasts regulate these processes is a rapidly growing area of research given the important implications for bone therapy, regenerative medicine, and hematopoietic stem cell transplantation. Here we summarize our current knowledge regarding the cellular and molecular crosstalk driving bone formation and hematopoiesis and will discuss the implications of a recent finding demonstrating that osteoblasts are a cellular source of erythropoietin .

Original publication

DOI

10.1007/s11914-014-0236-x

Type

Journal article

Journal

Curr Osteoporos Rep

Publication Date

12/2014

Volume

12

Pages

428 - 432

Keywords

Animals, Erythropoietin, Hematopoiesis, Humans, Models, Animal, Osteoblasts, Osteogenesis, Signal Transduction