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A tissue culture system for epithelial cells derived from male human foetal genital ducts has been established. The cells show morphological and biochemical characteristics of ductal epithelial cells, and can be passaged and maintained in culture for considerable periods of time. These cells will provide a suitable system for investigating, by electrophysiological, biochemical and molecular biological methods, the cause of sterility in cystic fibrosis.


Journal article


J Cell Sci

Publication Date



92 ( Pt 4)


687 - 690


Cells, Cultured, Culture Media, Cystic Fibrosis, Epididymis, Epithelium, Humans, Immunohistochemistry, Infertility, Male, Male, Mucins, Vas Deferens