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The binding properties of two lectins, concanavalin A and wheatgerm agglutinin to membrane glycoproteins extracted from cystic fibrosis fibroblasts have been examined. No differences were found between the binding patterns of either of these lectins to cystic fibrosis and normal fibroblast glycoproteins. The amount of concanavalin A binding to a glycoprotein of approximate Mr 150 000 has been shown to be related to the population doubling time of a cell culture at the time of analysis.

Type

Journal article

Journal

Clin Chim Acta

Publication Date

28/02/1983

Volume

128

Pages

41 - 51

Keywords

Adolescent, Adult, Cell Membrane, Cells, Cultured, Child, Child, Preschool, Concanavalin A, Cystic Fibrosis, Fibroblasts, Glycoproteins, Heterozygote, Humans, Infant, Lectins, Membrane Proteins, Middle Aged, Staining and Labeling, Wheat Germ Agglutinins