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Linkage studies have been carried out with 28 X-linked polymorphic probes to try to locate the gene for X-linked lymphoproliferative disease (XLP). DNA from three families has been analysed, including three affected boys among 21 family members. None of the probes tested has been found to be linked to XLP. However, the data are recorded for the use of other workers on this rare disease.


Journal article


Clin Genet

Publication Date





162 - 168


Chromosome Mapping, DNA, Female, Genetic Linkage, Humans, Immunologic Deficiency Syndromes, Lymphoproliferative Disorders, Male, Pedigree, Polymorphism, Genetic, Polymorphism, Restriction Fragment Length, X Chromosome