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Compared to external beam radiotherapy, targeted radionuclide therapy (TRT) allows for systemic radiation treatment of metastatic lesions. Published work on recent strategies to improve patient management and response to TRT through individualising patient treatment, modifying treatment pharmacokinetics and increasing anticancer potency are discussed in this review, with a special focus on the application of clinically evaluated radiolabelled ligands and peptides in the treatment of neuroendocrine and prostate cancers.

Original publication

DOI

10.3390/cancers11020268

Type

Journal article

Journal

Cancers (Basel)

Publication Date

25/02/2019

Volume

11

Keywords

neuroendocrine cancer, patient management, precision medicine, prostate cancer, targeted radionuclide therapy