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Publications

Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models

Kaeppler JR. et al, (2022), EMBO reports

Using oxygen dose histograms to quantify voxelised ultra-high dose rate (FLASH) effects in multiple radiation modalities.

Van den Heuvel F. et al, (2022), Phys Med Biol

Influence of ionizing radiation and cell density on the kinetics of autocrine destruction and intercellular induction of apoptosis in precancerous cells.

Abdelrazzak AB. et al, (2022), Sci Rep, 12

Review of the effect of reduced levels of background radiation on living organisms

Chew MT. et al, (2022), Radiation Physics and Chemistry

Oxidative stress and X-ray exposure levels-dependant survival and metabolic changes in murine HSPCs

Karabulutoglu M. et al, (2021), Antioxidants

Low dose ionising radiation-induced hormesis: Therapeutic implications to human health

Lau YS. et al, (2021), Applied Sciences (Switzerland), 11

Irradiation at ultra-high (FLASH) dose rates reduces acute normal tissue toxicity in the mouse gastrointestinal system.

Ruan J-L. et al, (2021), Int J Radiat Oncol Biol Phys

Quantifying the oxygen fixation mechanism in charged particle beams

Van den Heuvel F. et al, (2021), RADIOTHERAPY AND ONCOLOGY, 161, S1519 - S1519

Endothelial apoptosis after ionizing radiation mainly occurs in non-perfused vessels leaving vascular function intact

Markelc B. et al, (2021), FEBS OPEN BIO, 11, 93 - 94

USP9X is required to maintain cell survival in response to high-LET radiation

Nickson C. et al, (2021), Frontiers in Oncology

Incorporating oxygenation levels in analytical DNA–damage models — quantifying the oxygen fixation mechanism

Van den Heuvel F. et al, (2021), Physics in Medicine & Biology

Olaparib increases the therapeutic index of hemithoracic irradiation compared with hemithoracic irradiation alone in a mouse lung cancer model.

Jiang Y. et al, (2021), Br J Cancer, 124, 1809 - 1819

Ongoing repair of migration-coupled DNA damage allows planarian adult stem cells to reach wound sites.

Sahu S. et al, (2021), Elife, 10

Radiation, a two-edged sword: From untoward effects to fractionated radiotherapy

Chew MT. et al, (2021), Radiation Physics and Chemistry, 178

Induction of Genomic Instability in a Primary Human Fibroblast Cell Line Following Low-Dose Alpha-Particle Exposure and the Potential Role of Exosomes

Elbakrawy E. et al, (2020), Biology Open, 10

FLEPAC: A FLASH therapy treatment planning system for electrons, protons, Helium and Carbon ions.

Van den Heuvel F. et al, (2020), RADIOTHERAPY AND ONCOLOGY, 152, S326 - S327

Oxygen Related Factors in FLASH Radiotherapy

Van den Heuvel F. et al, (2020), INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 108, E534 - E534

The physical separation between the LET associated with the ultimate relative biological effect (RBE) and the maximum LET in a proton or ion beam

Jones B. and Hill MA., (2020), Biomedical Physics and Engineering Express, 6

ReN VM spheroids in matrix: A neural progenitor three-dimensional in vitro model reveals DYRK1A inhibitors as potential regulators of radio-sensitivity.

Wan X. et al, (2020), Biochem Biophys Res Commun

FLASH: Flash Leverages A Sudden Hypoxia

Von der Heuvel F. et al, (2020), MEDICAL PHYSICS, 47, E786 - E786

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