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Publications

Thinking inside the box: intracellular roles for complement system proteins come into focus

O’Brien RM. et al, (2023), British Journal of Cancer

Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy

Krieg C. et al, (2022), Journal for ImmunoTherapy of Cancer, 10, e004717 - e004717

The Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer.

Sodji QH. et al, (2022), Cancer Res Commun, 2, 725 - 738

The effects of radiation therapy on the macrophage response in cancer.

Beach C. et al, (2022), Front Oncol, 12

The importance of hypoxia in radiotherapy for the immune response, metastatic potential and FLASH-RT

OLCINA DEL MOLINO M. et al, (2021), International Journal of Radiation Biology

Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity.

Bader SB. et al, (2021), Nucleic Acids Res, 49, 7492 - 7506

Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis.

Olcina MM. et al, (2020), iScience, 23

The tumour microenvironment links complement system dysregulation and hypoxic signalling.

Olcina MM. et al, (2019), Br J Radiol, 92

Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer.

Olcina MM. et al, (2018), Cell Rep, 25, 3721 - 3732.e6

Reducing radiation-induced gastrointestinal toxicity - the role of the PHD/HIF axis.

Olcina MM. and Giaccia AJ., (2016), J Clin Invest, 126, 3708 - 3715

H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK.

Olcina MM. et al, (2016), Oncogene, 35, 793 - 799

Targeting chromatin to improve radiation response.

Olcina MM. et al, (2015), Br J Radiol, 88

Replication stress and chromatin context link ATM activation to a role in DNA replication.

Olcina MM. et al, (2013), Mol Cell, 52, 758 - 766

Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation.

Fokas E. et al, (2012), Cell Death Dis, 3