Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features.
Robbe P. et al, (2022), Nat Genet, 54, 1675 - 1689
Cellular Therapy in High-Risk Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter Syndrome.
Barbanti MC. et al, (2022), Front Oncol, 12
Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia.
Klintman J. et al, (2021), Blood, 137, 2800 - 2816
Comprehensive genomic testing for chronic lymphocytic leukaemia patients: WGS, one key to patient stratification
Ridout K. et al, (2020), LEUKEMIA & LYMPHOMA, 61, 167 - 168
Next-generation sequencing of TP53 mutations negates the need for FISH assessment in the investigation of TP53 aberrations
Catherwood MA. et al, (2020), LEUKEMIA & LYMPHOMA, 61, 197 - 198
The STELLAR trial protocol: a prospective multicentre trial for Richter's syndrome consisting of a randomised trial investigation CHOP-R with or without acalabrutinib for newly diagnosed RS and a single-arm platform study for evaluation of novel agents in relapsed disease.
Appleby N. et al, (2019), BMC Cancer, 19
FIP1L1-PDGFRα p.T674I-D842L: A Novel and Ponatinib Resistant Compound Mutation in FIP1L1-PDGFRα Positive Leukemia
Lierman E. et al, (2019), HemaSphere, 3
Highly Comprehensive Genomic Testing for CLL: WGS, One Key to CLL Patient Stratification
Ridout KE. et al, (2018), BLOOD, 132
Guideline for the treatment of chronic lymphocytic leukaemia: A British Society for Haematology Guideline.
Schuh AH. et al, (2018), Br J Haematol, 182, 344 - 359
Risk adjusted therapy in chronic lymphocytic leukemia: a phase II cancer trials Ireland (CTRIAL-IE [ICORG 07-01]) study of fludarabine, cyclophosphamide, and rituximab therapy evaluating response adapted, abbreviated frontline therapy with FCR in non-del(17p) CLL.
Appleby N. et al, (2018), Leuk Lymphoma, 59, 1338 - 1347
Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib.
Bye AP. et al, (2017), Blood Adv, 1, 2610 - 2623
Clinical and laboratory assessment of a patient with thrombocytosis.
Appleby N. and Angelov D., (2017), Br J Hosp Med (Lond), 78, 558 - 564
Reversal of warfarin anticoagulation using prothrombin complex concentrate at 25 IU kg-1 : results of the RAPID study.
Appleby N. et al, (2017), Transfus Med, 27, 66 - 71
Symptomatic BK virus reactivation following fludarabine, cyclophosphamide and rituximab chemotherapy for chronic lymphocytic leukemia/small lymphocytic lymphoma.
Appleby N. et al, (2014), Leuk Lymphoma, 55, 1181 - 1183
Efficacy and safety of once daily low molecular weight heparin (tinzaparin sodium) in high risk pregnancy.
Ní Ainle F. et al, (2008), Blood Coagul Fibrinolysis, 19, 689 - 692