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Primary Objective

    • To identify the clinical, genomic and immunological predictive markers of progression to malignant disease

    Secondary Objectives

      • To assess Quality of Life of patients with pre-cancerous lymphoid conditions
      • To study other clinical complications associated with pre-malignancy (infection, bony fractures, thrombosis and deaths not to progression to lymphoid cancers)
      • To establish evidence-based guidance for monitoring and follow-up of patients with pre-cancerous conditions

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