Objectives
Primary Objective
- To identify the clinical, genomic and immunological predictive markers of progression to malignant disease
Secondary Objectives
- To assess Quality of Life of patients with pre-cancerous lymphoid conditions
- To study other clinical complications associated with pre-malignancy (infection, bony fractures, thrombosis and deaths not to progression to lymphoid cancers)
- To establish evidence-based guidance for monitoring and follow-up of patients with pre-cancerous conditions


