Research groups
Research Theme
Tumour Microenvironment (Lead Principal Investigator)
Websites
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redOx⇌KCL
Collaborative interdisciplinary programme funded by the EPSRC
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RadNet seminar by Prof. Hammond
Watch on YouTube
Colleges
Ester Hammond
Professor of Molecular Cancer Biology
- TME Research Theme lead, Department of Oncology
- Director of the Oxford-MRC Doctoral Training Partnership
Research Summary
I investigate how tumours survive in conditions which include low oxygen (hypoxia). The goal is to target the hypoxic parts of tumours to improve cancer therapy.
Biography
Ester completed her PhD at the School for Cancer Sciences, University of Birmingham then accepted a post as a postdoctoral fellow within the Molecular Oncology Group at the University of Cambridge School of Clinical Medicine before moving to the USA to join the Department of Radiation Oncology at Stanford University, first as a postdoctoral fellow then a research associate. She joined the Department in 2007.
GROUP MEMBERS
GROUP ALUMNI & NEXT DESTINATIONS
Sam Bader (2016-21), DPhil student - Scientist, Totus Medicines, USA
Charlotte Simpson (2020-2021) MRes student - PhD student, University of Cambridge, UK
Natalie Ng, (2016–21), DPhil student - Scientist, Oxford Biomedica, UK
Anna Mandel, (2018-20), MRes student - PhD student, University of Toronto, Canada
Ania Skwarska, (2019-20) Postdoctoral Researcher - Postdoctoral Researcher Medical University of Bialystok, Poland
Elizabeth Bowler, (2019 -20) Postdoctoral Researcher - Postdoctoral Researcher University of Bath
Ming-Shih Hwang, (2018-19), Postdoctoral Researcher - Postdoctoral Researcher, The Francis Crick Institute
Karen Sayal, (2018-19), Clinical Research Fellow – CRF, University of Oxford
Katarzyna Leszczynska, (2011 – 18), Postdoctoral Researcher, - Postdoctoral Researcher Nencki Institute, Warsaw, Poland
Alhasan Al-Habib (2017), MSc Student - PhD student, Cambridge University, UK
Karin Purshouse (2016-17), ACF - ACF, Oxford University Hospitals Trust, UK
Greg Dobrynin (2014-17), Postdoctoral Researcher - Senior Scientist, Immunocore Ltd, UK
Iosifina Foskolou (2012-16), DPhil Student - Postdoctoral Researcher, Cambridge University, UK
Liam O'Connor (2012-16), DPhil Student - Patent lawyer, UK
Cindy Korner (2010-15), MSc/DPhil Student - Postdoctoral Researcher, Karolinska Institute, Sweden
Selva Anbalagan (2009-14), MSc/DPhil Student - Postdoctoral Researcher, ICR, London, UK
Monica Olcina (2009-14), MSc/DPhil Student - Postdoctoral Researcher, Stanford University, US
Isabel Pires (2007-12), Postdoctoral Researcher - Lecturer, University of Hull, UK
Recent publications
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Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
Journal article
MA T. et al, (2023), Nucleic Acids Research
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Corrigendum to "A DNA-structured mathematical model of cell-cycle progression in cyclic hypoxia" [J. Theor. Biol. 545 (2022) 111104].
Journal article
Celora GL. et al, (2023), J Theor Biol
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Oxali(IV)Fluors: Fluorescence Responsive Oxaliplatin(IV) Complexes Identify a Hypoxia-Dependent Reduction in Can-cer Cells
Journal article
Boulet M. et al, (2023), Journal of the American Chemical Society
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Data from Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
Other
Rodriguez-Berriguete G. et al, (2023)
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Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models.
Journal article
Rodriguez-Berriguete G. et al, (2023), Clin Cancer Res, 29, 1631 - 1642
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Supplementary Figure S1 from Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
Other
Rodriguez-Berriguete G. et al, (2023)
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Supplementary Figure S1 from Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
Other
Rodriguez-Berriguete G. et al, (2023)
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Supplementary Figure S2 from Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
Other
Rodriguez-Berriguete G. et al, (2023)