Research groups
Research Theme
Tumour Microenvironment (Lead Principal Investigator)
Websites
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redOx⇌KCL
Collaborative interdisciplinary programme funded by the EPSRC
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RadNet seminar by Prof. Hammond
Watch on YouTube
Colleges
Ester Hammond
Professor of Molecular Cancer Biology
- TME Research Theme lead, Department of Oncology
- Director of the Oxford-MRC Doctoral Training Partnership
Research Summary
I investigate how tumours survive in conditions which include low oxygen (hypoxia). The goal is to target the hypoxic parts of tumours to improve cancer therapy.
Biography
Ester completed her PhD at the School for Cancer Sciences, University of Birmingham then accepted a post as a postdoctoral fellow within the Molecular Oncology Group at the University of Cambridge School of Clinical Medicine before moving to the USA to join the Department of Radiation Oncology at Stanford University, first as a postdoctoral fellow then a research associate. She joined the Department in 2007.
GROUP MEMBERS
RECENT GROUP ALUMNI & NEXT DESTINATIONS
Louise Martin (2023-2024) Research Assistant - DPhil student University of Oxford, UK
Çağla Tosun (2020-2024) DPhil student/Postdoctoral Researcher - Postdoctoral Researcher University of Nottingham, UK
Tiffany Ma (2018-23), DPhil student/Postdoctoral Researcher - Precision Immunomics Scientist Infinitopes, UK
Sam Bader (2016-21), DPhil student - Scientist, Totus Medicines, USA
Charlotte Simpson (2020-2021) MRes student - PhD student, University of Cambridge, UK
Natalie Ng, (2016–21), DPhil student - Scientist, Oxford Biomedica, UK
Anna Mandel, (2018-20), MRes student - PhD student, University of Toronto, Canada
Ania Skwarska, (2019-20) Postdoctoral Researcher - Postdoctoral Researcher Medical University of Bialystok, Poland
Elizabeth Bowler, (2019 -20) Postdoctoral Researcher - Postdoctoral Researcher University of Bath
Recent publications
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ZBTB7A forms a heterodimer with ZBTB2 and inhibits ZBTB2 homodimerization required for full activation of HIF-1
Journal article
Kambe G. et al, (2024), Biochemical and Biophysical Research Communications
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Journal article
Twigger S. et al, (2024), Redox Biology
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Fluorogenic Platinum(IV) Complexes as Potential Predictors for the Design of Hypoxia-Activated Platinum(IV) Prodrugs
Journal article
HAMMOND E., (2024), Dalton Transactions
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Journal article
Martin LAW. and Hammond EM., (2024), Frontiers for Young Minds, 12
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Antibody-based Imaging of Bioreductive Prodrug Release in Hypoxia
Journal article
Tosun C. et al, (2023), JACS Au
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Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
Journal article
MA T. et al, (2023), Nucleic Acids Research
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Journal article
Celora GL. et al, (2023), J Theor Biol, 571
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Journal article
Leszczynska KB. et al, (2023), Mol Oncol, 17, 1173 - 1191