Tumour Microenvironment (Lead Principal Investigator)
Professor of Molecular Cancer Biology
- Senior Group Leader at the Oxford Institute for Radiation Oncology
I investigate how tumours survive in conditions which include low oxygen (hypoxia). The goal is to target the hypoxic parts of tumours to improve cancer therapy.
Ester completed her PhD at the School for Cancer Sciences, University of Birmingham then accepted a post as a postdoctoral fellow within the Molecular Oncology Group at the University of Cambridge School of Clinical Medicine before moving to the USA to join the Department of Radiation Oncology at Stanford University, first as a postdoctoral fellow then a research associate.
She joined the Oxford Institute in 2007 as a CRUK junior group leader.
GROUP ALUMNI & NEXT DESTINATIONS
Alhasan Al-Habib (2017), MSc Student - PhD student, Cambridge University, UK
Karin Purshouse (2016-17), ACF - ACF, Oxford University Hospitals Trust, UK
Greg Dobrynin (2014-17), Postdoctoral Researcher - Senior Scientist, Immunocore Ltd, UK
Iosifina Foskolou (2012-16), DPhil Student - Postdoctoral Researcher, Cambridge University, UK
Liam O'Connor (2012-16), DPhil Student - Patent lawyer, UK
Cindy Korner (2010-15), MSc/DPhil Student - Postdoctoral Researcher, Karolinska Institute, Sweden
Selva Anbalagan (2009-14), MSc/DPhil Student - Postdoctoral Researcher, ICR, London, UK
Monica Olcina (2009-14), MSc/DPhil Student - Postdoctoral Researcher, Stanford University, US
Isabel Pires (2007-12), Postdoctoral Researcher - Lecturer, University of Hull, UK
Collins SL. et al, (2018), ACS Chem Biol
Carruthers RD. et al, (2018), Cancer Res, 78, 5060 - 5071
Hypoxia activated small molecule induced gene expression
Collins S. et al, (2018), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256
Hypoxia-activated prodrugs of the KDAC inhibitor panobinostat
Calder E. et al, (2018), ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256
Jennings LE. et al, (2018), Bioorg Med Chem, 26, 2937 - 2957