Research groups
External Funding
Medical Research Council (MRC)
National Institutes of Health (NIH)
Collaborators
Professor Crister Ceberg, Lund University
Dr Karl Butterworth, Queen's University Belfast
Dr Jason Parsons, University of Birmingham
Dr Betina Børresen, University of Copenhagen
Dr Anders E Hansen, Technical University of Denmark
Professor Constantinos Koumenis, University of Pennsylvania
Dr Amir Abdollahi, University of Heidelberg
Professor Kaye Williams, University of Manchester
Professor Anthony Chalmers, University of Glasgow
Kristoffer Petersson
PhD
MRC Investigator & Group Leader - FLASH Radiation
RESEARCH SUMMARY
FLASH radiation is a novel radiotherapy technique that show great potential in improving cancer treatment. However, very little is known about the biological mechanisms behind the highly beneficial FLASH effect. The research group aims to identify these mechanisms, explain the effect, and to find the optimal way of implementing the technique in clinical practice.
BIOGRAPHY
Kristoffer is a Medical physicist from Helsingborg, Sweden, and holds a M.Sc. (2009) and a Ph.D. (2014) in Medical Radiation Physics from Lund University, Sweden. Kristoffer enjoyed a Post-doc period (2014-2017) working on FLASH radiation at CHUV, in Lausanne, Switzerland. Lately, he has worked as a clinical medical physicist (2017-2019) and started his own research group in FLASH radiotherapy (2017-) at Skåne University Hospital. Since 2019, Kristoffer is Group leader of the research group "Physics and Biology of FLASH Radiation" in the Department of Oncology.
GROUP MEMBERS
Nathalie Lövgren, DPhil Student
Salomé Paillas, Postdoctoral Researcher
Jia-Ling Ruan, Postdoctoral Researcher
Sovan Sarkar, Postdoctoral Researcher
Michele Szegda, MSc student
Edward Taylor, DPhil Student
Iain Tullis, Postdoctoral Researcher & Lab manager
GROUP ALUMNI & NEXT DESTINATIONS
Dr Christian Cooper, Postdoctoral Researcher (2023-2024) --> Research Scientist at Granza Bio
Lana Hendrawan, Research Assistant (2023-2024) -->
Recent publications
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Photon FLASH spares radiation-induced changes in cardiac function, remodelling and arrythmia in a preclinical model.
Journal article
Ghita-Pettigrew M. et al, (2026), Radiother Oncol, 216
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Quantifying the flash effect and its dependence on average dose rate in vivo for 6 MeV electron and 6 MV photon beams.
Journal article
Paillas S. et al, (2026), Clin Transl Radiat Oncol, 56
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Stable electron-irradiated [1-13C]alanine radicals for metabolic imaging with dynamic nuclear polarization.
Journal article
Rooney CHE. et al, (2025), Sci Adv, 11
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Tissue-specific iron levels modulate lipid peroxidation and the FLASH radiotherapy effect.
Journal article
Vilaplana-Lopera N. et al, (2025), Cell Death Dis, 16
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Not All Tumors Are Alike: Varying Efficacy of FLASH Across Tumor Types and Oxygenation Status in Spheroid Models.
Journal article
Dela R. et al, (2025), Br J Radiol
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Investigating the therapeutic potential of FLASH radiotherapy - a treatment planning study.
Journal article
Hörberger F. et al, (2025), Radiother Oncol, 209
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First in vitro and in vivo experiments with ultra high-dose rate oxygen ion radiotherapy.
Journal article
Karle C. et al, (2025), Phys Imaging Radiat Oncol, 35
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FLASH-induced DNA damage reduction measured in vitro correlates with effective oxygen depletion determined in silico: further support for oxygen depletion contributing to FLASH's reduced damage burden in vitro.
Journal article
Rothwell B. et al, (2025), Br J Radiol, 98, 1032 - 1037
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Megavoltage photon FLASH for preclinical experiments.
Journal article
Taylor ERJF. et al, (2025), Med Phys, 52
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Recent Innovations to Foster Personalized Adaptive Radiation Therapy.
Journal article
Harms J. et al, (2025), Int J Radiat Oncol Biol Phys, 122, 528 - 531