Research groups
External Funding
Medical Research Council (MRC)
National Institutes of Health (NIH)
Collaborators
Professor Crister Ceberg, Lund University
Dr Karl Butterworth, Queen's University Belfast
Dr Jason Parsons, University of Birmingham
Dr Betina Børresen, University of Copenhagen
Dr Anders E Hansen, Technical University of Denmark
Professor Constantinos Koumenis, University of Pennsylvania
Dr Amir Abdollahi, University of Heidelberg
Professor Kaye Williams, University of Manchester
Professor Anthony Chalmers, University of Glasgow
Kristoffer Petersson
PhD
MRC Investigator & Group Leader - FLASH Radiation
RESEARCH SUMMARY
FLASH radiation is a novel radiotherapy technique that show great potential in improving cancer treatment. However, very little is known about the biological mechanisms behind the highly beneficial FLASH effect. The research group aims to identify these mechanisms, explain the effect, and to find the optimal way of implementing the technique in clinical practice.
BIOGRAPHY
Kristoffer is a Medical physicist from Helsingborg, Sweden, and holds a M.Sc. (2009) and a Ph.D. (2014) in Medical Radiation Physics from Lund University, Sweden. Kristoffer enjoyed a Post-doc period (2014-2017) working on FLASH radiation at CHUV, in Lausanne, Switzerland. Lately, he has worked as a clinical medical physicist (2017-2019) and started his own research group in FLASH radiotherapy (2017-) at Skåne University Hospital. Since 2019, Kristoffer is Group leader of the research group "Physics and Biology of FLASH Radiation" in the Department of Oncology.
GROUP MEMBERS
Nathalie Lövgren, DPhil Student
Salomé Paillas, Postdoctoral Researcher
Jia-Ling Ruan, Postdoctoral Researcher
Sovan Sarkar, Postdoctoral Researcher
Michele Szegda, MSc student
Edward Taylor, DPhil Student
Iain Tullis, Postdoctoral Researcher & Lab manager
GROUP ALUMNI & NEXT DESTINATIONS
Dr Christian Cooper, Postdoctoral Researcher (2023-2024) --> Research Scientist at Granza Bio
Lana Hendrawan, Research Assistant (2023-2024) -->
Recent publications
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First in vitro and in vivo experiments with ultra high-dose rate oxygen ion radiotherapy
Journal article
Karle C. et al, (2025), Physics and Imaging in Radiation Oncology, 100803 - 100803
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Recent Innovations to Foster Personalized Adaptive Radiation Therapy.
Journal article
Harms J. et al, (2025), Int J Radiat Oncol Biol Phys, 122, 528 - 531
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Investigating the therapeutic potential of FLASH radiotherapy - a treatment planning study.
Journal article
Hörberger F. et al, (2025), Radiother Oncol, 209
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Megavoltage photon FLASH for preclinical experiments.
Journal article
Taylor ERJF. et al, (2025), Med Phys
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FLASH-induced DNA damage reduction measured in vitro correlates with effective oxygen depletion determined in silico: further support for oxygen depletion contributing to FLASH's reduced damage burden in vitro.
Journal article
Rothwell B. et al, (2025), Br J Radiol
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Oxygen consumption measurements at ultra-high dose rate over a wide LET range.
Journal article
Karle C. et al, (2025), Med Phys, 52, 1323 - 1334
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The AsiDNA™ decoy mimicking DSBs protects the normal tissue from radiation toxicity through a DNA-PK/p53/p21-dependent G1/S arrest.
Journal article
Sesink A. et al, (2024), NAR Cancer, 6
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Reconfiguring a Plane-Parallel Transmission Ionization Chamber to Extend the Operating Range into the Ultra-High Dose-per-pulse Regime.
Journal article
Konradsson E. et al, (2024), Radiat Res
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Beam control system and output fine-tuning for safe and precise delivery of FLASH radiotherapy at a clinical linear accelerator
Journal article
Konradsson E. et al, (2024), Frontiers in Oncology, 14
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Comparable survival in rats with intracranial glioblastoma irradiated with single-fraction conventional radiotherapy or FLASH radiotherapy
Journal article
Liljedahl E. et al, (2024), Frontiers in Oncology, 13