Callum Beach - DPhil (joint student with Prof Tim Maughan and Prof Simon Leedham)
David MacLean - Research Assistant
Dominika Majorova - Research Assistant
Kelly Lee - MRes Student (joint student with Prof Hammond)
Group Leader - Immune Radiation Biology
Interested in understanding how tumours exploit innate immune pathways to their advantage, and studying how we can target these pathways to improve radiotherapy
Monica Olcina studied Pharmacy at the University of Manchester. After completing the required training to become a registered pharmacist she moved to Oxford to undertake her Masters and DPhil studies in Radiation Biology. In 2014, she joined Stanford University where she worked as a Cancer Research Institute Irvington Postdoctoral Fellow to identify novel pathways that could be targeted to improve radiotherapy. In 2019 she moved to the University of Zurich to continue these studies. In December 2020 she joined the Oxford Institute for Radiation Oncology as a Junior Group Leader.
MRC RESEARCH PROGRAMME:
The importance of hypoxia in radiotherapy for the immune response, metastatic potential and FLASH-RT
OLCINA DEL MOLINO M. et al, (2021), International Journal of Radiation Biology
Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis.
Olcina MM. et al, (2020), iScience, 23
The tumour microenvironment links complement system dysregulation and hypoxic signalling.
Olcina MM. et al, (2019), Br J Radiol, 92
Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer.
Olcina MM. et al, (2018), Cell Rep, 25, 3721 - 3732.e6
Reducing radiation-induced gastrointestinal toxicity - the role of the PHD/HIF axis.
Olcina MM. and Giaccia AJ., (2016), J Clin Invest, 126, 3708 - 3715
H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK.
Olcina MM. et al, (2016), Oncogene, 35, 793 - 799