Contact information
olivier.zanier@oncology.ox.ac.uk
Old Road Campus Research Building, Roosevelt Drive, Oxford, UK
Research groups
Olivier Zanier
MMed
DPhil student
Research
I investigate novel treatment agents for paediatric high-grade gliomas (pHGG), highly aggressive brain tumours in children for which very limited therapeutic options exist. My work focuses on exploring drugs that induce reactive oxygen species (ROS) as well as a hypoxia-activated HDAC inhibitor, particularly in combination with radiotherapy and under hypoxic conditions - a key feature of the tumour microenvironment.
My research is supervised by Prof Hammond and Dr Olcina. It is part of HIT-GLIO, an international consortium of researchers dedicated to enhancing the quality of life for pHGG patients and their families.
My studies are generously supported by the University of Oxford through a Clarendon Fund Scholarship and a Medical Sciences Postgraduate Studentship.
Biography
Before moving to Oxford, I studied medicine at the University of Zurich in Switzerland, where my research as part of the MICN-Lab focused on the intersection of neurosurgery and machine learning. As a physician-scientist, I aim to bridge the gap between research and clinical application with the goal of ultimately advancing patient care for neuro-oncological patients.
Recent publications
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Strategies for generating synthetic computed tomography-like imaging from radiographs: A scoping review
De Wilde D. et al, (2025), Medical Image Analysis, 101
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Fully automated grading of pituitary adenoma
Da Mutten R. et al, (2025), NeuroImage: Reports, 5
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TomoRay: Generating Synthetic Computed Tomography of the Spine From Biplanar Radiographs.
Zanier O. et al, (2024), Neurospine, 21, 68 - 75
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Whole Spine Segmentation Using Object Detection and Semantic Segmentation.
Da Mutten R. et al, (2024), Neurospine, 21, 57 - 67
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From molecular signatures to radiomics: tailoring neurooncological strategies through forecasting of glioma growth.
Rauch P. et al, (2024), Neurosurg Focus, 56