Gastric cancer
Smyth E., Filippi B.
Gastric cancer (GC) is the fifth most common cancer worldwide and is a poor prognosis disease. GC is diagnosed by endoscopic biopsy and staged with CT scan, endoscopic ultrasound, and laparoscopy. An MDT approach is of major importance to plan a tailored-made treatment for GC patients. Very early GCs are treated with endoscopic resection, while locally advanced GCs are treated with radical surgery accompanied by perioperative chemotherapy or adjuvant chemotherapy or chemoradiotherapy when appropriate. The management of advanced GCs is based on sequential lines of systemic treatments that include combination of chemotherapies, targeted therapies, or immunotherapies. The possible benefit of local treatments in advanced disease still needs to be clarified.