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CNS involvement is a common feature of metastatic melanoma. Despite this, there is little evidence upon which clinicians can base decisions about treatment. The short prognosis and significant symptoms usually associated with melanoma brain metastases have excluded these patients from clinical trials. In Europe the standard treatment involves whole brain radiotherapy, although selected centers offer other modalities, including surgery, radiosurgery, and chemotherapy.

Type

Journal article

Journal

Semin Oncol

Publication Date

10/2002

Volume

29

Pages

513 - 517

Keywords

Antineoplastic Agents, Brain Neoplasms, Combined Modality Therapy, Cranial Irradiation, Humans, Melanoma, Radiosurgery, Skin Neoplasms