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SYCP3 localizes to the lateral elements of the synaptonemal complex and is essential for male meiosis. The genomic structure of SYCP3 consists of nine exons spanning approximately 14 kb. In mouse and rat, but not in hamster, the putative translation start of SYCP3 is present in the first exon. The putative promoter of SYCP3 was also cloned and shown to drive transcription of a reporter gene in somatic cells.

Type

Journal article

Journal

Biochim Biophys Acta

Publication Date

16/04/2001

Volume

1518

Pages

294 - 299

Keywords

3T3 Cells, Amino Acid Sequence, Animals, Base Sequence, Exons, Introns, Meiosis, Mice, Molecular Sequence Data, Nuclear Proteins, Promoter Regions, Genetic, Synaptonemal Complex, Transfection