Figure 4 from Targeting c-MET for Endoscopic Detection of Dysplastic Lesions within Barrett’s Esophagus Using EMI-137 Fluorescence Imaging
Huang Y-J., Rieder J., Tan KV., Tenditnaya A., Vojnovic B., Gorpas D., Quante M., Vallis KA.
<p>Real-time FME imaging of L2-IL1β mouse after injection of EMI-137: <b>A,</b> Representative white-light, fluorescence, and overlay images of L2-IL1β mice with different lesion scores after EMI-137 injection. <b>B,</b> Normalized fluorescence signal intensities of the lesion and background in low- (<i>n</i> = 16 frames), intermediate- (<i>n</i> = 15 frames), and high-score (<i>n</i> = 8 frames) groups. <b>C,</b> Increased TBR in low-, intermediate- and high-score groups after EMI-137 injection compared with controls receiving PBS. ***, <i>P</i> < 0.001. AU, Arbitary unit; S<sub>bkg,</sub> signal intensities of the background; S<sub>lesion,</sub> signal intensities of the lesion.</p>