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Parity and lactation have long been recognised as protective factors in breast cancer, with notable risk reduction in triple negative breast cancer (TNBC). Recent work by Virassamy et al. suggests a tissue-specific, persistent immune surveillance underpins this effect, particularly in women who have also breastfed.

Original publication

DOI

10.1016/j.it.2025.12.004

Type

Journal article

Journal

Trends Immunol

Publication Date

01/2026

Volume

47

Pages

3 - 5

Keywords

breast cancer, infection, lactation, parity, resident memory T cells, Humans, Female, Lactation, Breast Neoplasms, Breast Feeding, Animals, Triple Negative Breast Neoplasms