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THE value of data from laboratory animals for the interpretation of the incidence of congenital abnormalities in human beings was first pointed out some time ago by Wright1. Results I have obtained from a balanced two-point backcross linkage experiment in the mouse have shown an effect of maternal age both on viability and recombination. The purpose of this communication is to present these results and discuss their implications for similar phenomena in human beings. © 1961 Nature Publishing Group.

Original publication

DOI

10.1038/1901134a0

Type

Journal article

Journal

Nature

Publication Date

01/12/1961

Volume

190

Pages

1134 - 1135