Research groups
Research Themes
Genome Integrity & Epigenetics (Collaborator)
COLLABORATORS
Colleges
Nick La Thangue
Professor of Cancer Biology
- Professorial Fellow, Linacre College
Research Summary
My research focusses on the mechanisms that give rise to the abnormal proliferation characteristic of tumour cells.
Biography
Nicholas La Thangue is Professor of Cancer Biology in the Department of Oncology, and was previously Cathcart Professor of Biochemistry at the University of Glasgow, and before that a scientist at the Medical Research Council.
He is a Fellow of the Royal Society of Edinburgh, a Member of the European Molecular Biology Organisation (EMBO), a Fellow of the Academy of Medical Sciences, a Fellow of the European Academy of Cancer Sciences, a Fellow of the Lister Institute and Professorial Fellow at Linacre College Oxford.
He has founded several biotech companies, most recently Oxford Cancer Biomarkers.
GROUP MEMBERS
GROUP ALUMNI & NEXT DESTINATIONS
Recent publications
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Sustained cancer-relevant alternative RNA splicing events driven by PRMT5 in high-risk neuroblastoma.
Bate-Eya LT. et al, (2024), Mol Oncol
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Citrullination and the protein code: crosstalk between post-translational modifications in cancer.
Harada K. et al, (2023), Philos Trans R Soc Lond B Biol Sci, 378
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Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response.
Barczak W. et al, (2023), Nat Commun, 14
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The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity.
Liu G. et al, (2023), Commun Biol, 6
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CXD101 and nivolumab in patients with metastatic microsatellite-stable colorectal cancer (CAROSELL): a multicentre, open-label, single-arm, phase II trial.
Saunders MP. et al, (2022), ESMO Open, 7