Contact information
mark.middleton@oncology.ox.ac.uk
+44 (0)1865 617331 (PA)
Debby Scott
debby.scott@oncology.ox.ac.uk
Research groups
Research Themes
Genome Integrity & Epigenetics (Collaborator)
Immunology (Collaborator)
Mark Middleton
Head, Department of Oncology
- Professor of Experimental Cancer Medicine
- Consultant Medical Oncologist, Oxford Cancer and Haematology Centre
Research Summary
My research concentrates on the development of new cancer drugs and on the treatment of melanoma and upper gastrointestinal tract cancers.
Biography
Mark Middleton is Professor of Experimental Cancer Medicine in the Department of Oncology, consultant Medical Oncologist at the Oxford Cancer and Haematology Centre and Head of the Department of Oncology at the University of Oxford.
Mark was the Lead Cancer Clinician for the Oxford University Hospitals NHS Foundation Trust (2012 -2017) directed the Early Phase Cancer Trials Unit. He is Director of the Cancer Research UK Oxford Centre and co-leader of the Cancer Theme in the NIHR Biomedical Research Centre.
He studied medicine at Cambridge and Oxford and trained in medical oncology at the Christie Hospital. Mark has overseen the development of internationally leading melanoma and upper GI clinical research groups and establishment of portfolios of early phase radiotherapy and haematooncology trials in Oxford. He is involved in the evaluation of novel immunotherapeutics, including pre-clinical development, trial design, proof of mechanism and proof of concept.
In his role as Cancer Centre director, Mark has established a new Doctoral Training Programme, for a DPhil in Cancer Science, offering non-clinical, medical student and clinical fellowships and programmes for post-doctoral research.
GROUP MEMBERS
Recent publications
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Journal article
SIVAKUMAR S. et al, (2021), Molecular Biomarkers and Precision Medicine for Pancreatic, Liver and Biliary Tract Cancers
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Long-term real-world experience with ipilimumab and non-ipilimumab therapies in advanced melanoma: the IMAGE study
Journal article
Dalle S. et al, (2021), BMC Cancer
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Long-term real-world experience with ipilimumab and non-ipilimumab therapies in advanced melanoma: the IMAGE study
Journal article
Dalle S. et al, (2021), BMC Cancer
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Journal article
Ye W. et al, (2021), Br J Cancer
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Tumour gene expression signature in primary melanoma predicts long-term outcomes
Journal article
Garg M. et al, (2021), Nature Communications