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Colorectal cancer is one of the commonest causes of cancer death worldwide. Surgery is the mainstay of treatment for disease that has not metastasized. This is often followed by adjuvant chemotherapy to reduce the chances of recurrence. Chemotherapy can also be used in advanced disease to palliate symptoms and extend life. Radiotherapy is used primarily for rectal cancer to control disease locally. This chapter describes the basics about colorectal cancer, surgery, chemotherapy, radiotherapy, and the use of newer biological agents. © 2012 Blackwell Publishing Ltd.

Original publication




Journal article

Publication Date



444 - 454